[AIIA 2022] Fast and accessible fabrication methodology for organ-on-a-chip devices

Organ-on-a-chip technology promises to revolutionize the next generation of personalized medicine by providing a human-derived platform to study human disease. However, the fabrication of these devices is a time-consuming and expensive task. Here we propose a streamlined fabrication methodology to produce these devices within hours, using only benchtop equipment and off-the-shelf materials. The low cost of this technology could be the much-needed change towards affordable organ-on-a-chip technology, serving as a facilitator for its dissemination and potentially replacing the dependency on experimental animal models, in close alignment with the 3Rs principles.

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